Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human GOSR1. AA range:11-60
Specificity
GS28 Polyclonal Antibody detects endogenous levels of GS28 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport.,similarity:Belongs to the GOSR1 family.,subcellular location:Enriched on vesicular components at the terminal rims of the Golgi.,subunit:Interacts with GABARAPL2. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR2, STX5 and YKT6.,
Protein name
Golgi SNAP receptor complex member 1
Other name
GOSR1; GS28; Golgi SNAP receptor complex member 1; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28; GOS-28
Fields
>>SNARE interactions in vesicular transport
Human protein sequence Database
O95249
Mouse protein sequence database
O88630
Rat protein sequence database
Cellular localization
Golgi apparatus membrane ; Single-pass type IV membrane protein . Localizes throughout the Golgi apparatus, with lowest levels in the trans-Golgi network (By similarity). Enriched on vesicular components at the terminal rims of the Golgi. Found in Golgi microtubules at low temperature (15 degrees Celsius). .
Tissue expression
Colon carcinoma,Prostate,Testis,Umbilical cord blood,
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