Molecular weight (DA)
30kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AIBP. AA range:121-170
Specificity
AI-BP Polyclonal Antibody detects endogenous levels of AI-BP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro by incubating cells with apoA-I. The human genome contains related pseudogenes. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 1 YjeF N-terminal domain.,subunit:Interacts with APOA1 and APOA2.,tissue specificity:Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level).,
Protein name
NAD(P)H-hydrate epimerase
Other name
APOA1BP; AIBP; YJEFN1; NAD(P)H-hydrate epimerase; Apolipoprotein A-I-binding protein; AI-BP; NAD(P)HX epimerase; YjeF N-terminal domain-containing protein 1; YjeF_N1
Human protein sequence Database
Q8NCW5
Mouse protein sequence database
Q8K4Z3
Rat protein sequence database
B0BNM1
Cellular localization
Mitochondrion . Secreted . In sperm, secretion gradually increases during capacitation. .
Tissue expression
Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level).
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