Molecular weight (DA)
25kD
Immunogen
Synthesized peptide derived from Latexin . at AA range: 90-170
Specificity
Latexin Polyclonal Antibody detects endogenous levels of Latexin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. [provided by RefSeq, Oct 2008],
Function
function:Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4.,similarity:Belongs to the protease inhibitor I47 (latexin) family.,tissue specificity:Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.,
Other name
LXN; Latexin; Endogenous carboxypeptidase inhibitor; ECI; Protein MUM; Tissue carboxypeptidase inhibitor; TCI
Human protein sequence Database
Q9BS40
Mouse protein sequence database
P70202
Rat protein sequence database
Q64361
Cellular localization
Cytoplasm .
Tissue expression
Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.
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