Molecular weight (DA)
35kD
Immunogen
Synthesized peptide derived from the N-terminal region of human FAIM2.
Specificity
FAIM2 Polyclonal Antibody detects endogenous levels of FAIM2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,
Function
function:Protects cells uniquely from Fas-induced apoptosis.,similarity:Belongs to the BI1 family.,subunit:Interacts with TNFRSF6.,tissue specificity:Widely expressed. Expressed at high levels in the brain especially in the hippocampus.,
Protein name
Protein lifeguard 2
Other name
FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2
Human protein sequence Database
Q9BWQ8
Mouse protein sequence database
Q8K097
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Membrane raft . Cell junction, synapse, postsynaptic cell membrane .
Tissue expression
Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus.
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