Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140
Specificity
Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
Function
function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
Other name
SERPINB5; PI5; Serpin B5; Maspin; Peptidase inhibitor 5; PI-5
Fields
>>p53 signaling pathway;>>MicroRNAs in cancer
Human protein sequence Database
P36952
Mouse protein sequence database
P70124
Rat protein sequence database
P70564
Cellular localization
Secreted, extracellular space.
Tissue expression
Normal mammary epithelial cells.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车