Molecular weight (DA)
15kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Mammaglobin B. AA range:10-59
Specificity
Mammaglobin B Polyclonal Antibody detects endogenous levels of Mammaglobin B protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.,mass spectrometry: PubMed:9720917,similarity:Belongs to the secretoglobin family. Lipophilin subfamily.,subunit:Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head.,tissue specificity:Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland.,
Function
function:May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.,mass spectrometry: PubMed:9720917,similarity:Belongs to the secretoglobin family. Lipophilin subfamily.,subunit:Heterodimer of a lipophilin A and a lipophilin C (mammaglobin B) monomer associated head to head.,tissue specificity:Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland.,
Protein name
Mammaglobin-B
Abbreviation
Mammaglobin B
Other name
SCGB2A1; LIPHC; MGB2; UGB3; Mammaglobin-B; Lacryglobin; Lipophilin-C; Mammaglobin-2; Secretoglobin family 2A member 1
Human protein sequence Database
O75556
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Expressed in thymus, trachea, kidney, steroid responsive tissues (prostate, testis, uterus, breast and ovary) and salivary gland.
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