Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AVEN. AA range:301-350
Specificity
Aven Polyclonal Antibody detects endogenous levels of Aven protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Protects against apoptosis mediated by Apaf-1.,subcellular location:Associated with intracellular membranes.,subunit:Binds Apaf-1, BCL-2 and BAD (Bcl-xl).,tissue specificity:Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.,
Function
function:Protects against apoptosis mediated by Apaf-1.,subcellular location:Associated with intracellular membranes.,subunit:Binds Apaf-1, BCL-2 and BAD (Bcl-xl).,tissue specificity:Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.,
Protein name
Cell death regulator Aven
Other name
AVEN; Cell death regulator Aven
Human protein sequence Database
Q9NQS1
Mouse protein sequence database
Q9D9K3
Rat protein sequence database
Cellular localization
Endomembrane system; Peripheral membrane protein. Associated with intracellular membranes.
Tissue expression
Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.
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